Trifluoroacetic acid → Ethyl glycyl-3-methoxyphenylalaninate trifluoroacetate

Participants

Reaction Steps

To a 100-mL round-bottomed flask was added ethyl N-(tert-butoxycarbonyl)glycyl-3-methoxyphenylalaninate (812 mg, 2.13 mmol) and trifluoroacetic acid (5 mL, 67.3 mmol) in dichloromethane (5 mL). The reaction mixture was stirred at room temperature for 30 min. The solvent was removed in vacuo to give crude ethyl glycyl-3-methoxyphenylalaninate trifluoroacetate as a viscous oil which was used without purification.

Provenance & Evidence