反应详情

温度

0 °C

To a 100-mL round-bottomed flask was added ethyl N-(tert-butoxycarbonyl)glycyl-3-(2-methoxy-4-pyridinyl)alaninate (2.3 g, 6.03 mmol) and trifluoroacetic acid (8 mL, 108 mmol) in DCM (8 mL). The reaction mixture was stirred at 0° C. for 2 h. The solvent was removed in vacuo to give crude ethyl glycyl-3-(2-methoxy-4-pyridinyl)alaninate as a colorless tar, which was used without further purification.

1. customThe solvent was removed in vacuo