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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1972742Generated: November 3, 2026

Hydrochloric Acid → HCID 69302734, compound

https://huagongshe.com/reaction/1972742

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 58529406HCID 58529406—
SolventMethanolHCID 887—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 69302734HCID 69302734—

Reaction Steps

To a solution of tert-butyl 4-{4-[4-amino-5-(2-benzyl-2H-indazol-6-yl)pyrrolo[2,1-f][1,2,4]triazin-7-yl]-1,3-thiazol-2-yl}piperidine-1-carboxylate (586 mg, 0.97 mmol) in MeOH (4 mL) was added 4M HCl in dioxane (2 mL). The mixture was stirred at rt for 16 h. The mixture was concentrated to afford 577 mg (100%) of, the desired product, which was used without further characterization.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08431695B2
Source datasetuspto-grants-2013_04
ORD IDord-691aa289a73f4c87aa8f12af838799e7
Source noteuspto-grants-2013_04