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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 197280Generated: October 29, 2026

Chloride → 6'-Bromo-4-(difluoromethyl)spiro[cyclohexane-1,2'-inden]-1'(3'H)-one

https://huagongshe.com/reaction/197280

Reaction equation

Participants

RoleNameHCIDCharge
ReactantChlorideHCID 312—
ReactantNitrogenHCID 947—
ReactantTetrahydrofuranHCID 8028—
ReactantLithium ionHCID 28486—
ReactantMethyl 1-(4-bromo-2-iodobenzyl)-4-(difluoromethyl)cyclohexanecarboxylateHCID 67979661—
ReactantHCID 178461726HCID 178461726—
Product6'-Bromo-4-(difluoromethyl)spiro[cyclohexane-1,2'-inden]-1'(3'H)-oneHCID 67979478—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-85b5126aec224c2c8a404d22039aafbf
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)