HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-chloro-N,N-dimethylacetamide → HCID 58529882, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-chloro-N,N-dimethylacetamide | HCID 75886 | — |
| Reactant | HCID 58529777 | HCID 58529777 | — |
| Product | HCID 58529882 | HCID 58529882 | 85% |
Reaction Steps
In a manner similar to the procedure described for Example 369 and using 5-[2-(cyclobutylmethyl)-2H-indazol-6-yl]-7-piperidin-4-ylpyrrolo[2,1-f][1,2,4]triazin-4-amine and substituting dimethylcarbamyl chloride for 2-chloro-N,N-dimethylacetamide as starting materials, 60 mg, (85%) of the desired product was isolated. LC-MS [M+H]+=473.3, RT=2.55 min.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08431695B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-7539027749764b6f84e22c22e927cc89 |
| Source note | uspto-grants-2013_04 |