Sodium Methoxide → HCID 21492561, compound

HRID 1973053Notes

Reaction equation

HRID 1973053 reaction equation
Cl.Cl[C:3]([C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1)([C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)[C:4]1[NH:5][CH2:6][CH2:7][CH2:8][CH2:9][N:10]=1.[CH3:23][O-:24].[Na+]>CO>[CH3:23][O:24][C:3]([C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1)([C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)[C:4]1[NH:5][CH2:6][CH2:7][CH2:8][CH2:9][N:10]=1

Participants

4

Reactant 2

HCID 10942334Sodium MethoxideHCID 21492566HCID 21492566, compound

Product 1

HCID 21492561HCID 21492561, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

2-(Chlorodiphenylmethyl)-4,5,6,7-tetrahydro-1H-1,3-diazepine hydrochloride (0.003 mole) is stirred at room temperature for two days in dry methanol (25 ml) containing sodium methoxide (0.006 mole). After removal of the solvent the residue is dissolved in chloroform washed with water and dried over magnesium sulphate. Removal of the solvent gives the title compound.

Workup

  1. customAfter removal of the solvent the residue
  2. dissolutionis dissolved in chloroform
  3. washwashed with water
  4. dry with materialdried over magnesium sulphate
  5. customRemoval of the solvent

Sources & evidence

ORD record
ord-c0b2044b9f9a4ff18f518edda9f43e80
Source dataset
uspto-grants-1976_12
Patent number
US03996207

Reaction notes

Loading…