Piperazine → HCID 21492790, compound

HRID 1973127Notes

Reaction equation

HRID 1973127 reaction equation
Br[C:2]1[N:6]2[C:7]3[CH:22]=[CH:21][CH:20]=[CH:19][C:8]=3[C:9]([C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][N:14]=3)=[N:10][CH:11]([CH3:12])[C:5]2=[N:4][N:3]=1.[NH:23]1[CH2:28][CH2:27][NH:26][CH2:25][CH2:24]1>>[CH3:12][CH:11]1[N:10]=[C:9]([C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][N:14]=2)[C:8]2[CH:19]=[CH:20][CH:21]=[CH:22][C:7]=2[N:6]2[C:2]([N:23]3[CH2:28][CH2:27][NH:26][CH2:25][CH2:24]3)=[N:3][N:4]=[C:5]12

Participants

3

Reactant 2

HCID 4837PiperazineHCID 21492779HCID 21492779, compound

Product 1

HCID 21492790HCID 21492790, compound

Procedure

In the manner given in Example 1, 1-bromo-4-methyl-6-(2-pyridyl)-4H-s-triazolo[4,3-a][1,4]benzodiazepine is heated with piperazine to give 4-methyl-1-(piperazino)-6-(2-pyridyl)-4H-s-triazolo[4,3-a][1,4]benzodiazepine.

Sources & evidence

ORD record
ord-ec7cd7d24d9a405c82ee17606e394784
Source dataset
uspto-grants-1976_12
Patent number
US03996230

Reaction notes

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