HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → Bicyclo[3.1.1]heptane-3-methanamine, 2,6,6-trimethyl-, hydrochloride (1:1)
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Bicyclo(3.1.1)heptane-3-methanamine, 2,6,6-trimethyl- | HCID 106576 | — |
| Solvent | Pentane | HCID 8003 | — |
| Product | Bicyclo[3.1.1]heptane-3-methanamine, 2,6,6-trimethyl-, hydrochloride (1:1) | HCID 106575 | — |
Reaction Steps
120 g of the 3-aminomethylpinane thus obtained are dissolved in 1.3 l of pentane and dry hydrogen chloride is passed into the solution at from 0° to 5° C, whilst stirring. When free amine is no longer detectable, the crystals produced are filtered off and dried. 142 g of (+)-3-aminomethylpinane hydrochloride of optical rotation [α]D23 = +35.4° (c = 1, methanol) are obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03996246 |
| Source dataset | uspto-grants-1976_12 |
| ORD ID | ord-3420f9b116b44839898def9bc22edc18 |
| Source note | uspto-grants-1976_12 |