反应详情

120 g of the 3-aminomethylpinane thus obtained are dissolved in 1.3 l of pentane and dry hydrogen chloride is passed into the solution at from 0° to 5° C, whilst stirring. When free amine is no longer detectable, the crystals produced are filtered off and dried. 142 g of (+)-3-aminomethylpinane hydrochloride of optical rotation [α]D23 = +35.4° (c = 1, methanol) are obtained.

1. customis passed into the solution at from 0° to 5° C
2. customthe crystals produced
3. filtrationare filtered off
4. customdried