反应详情

A mixture of 10 g. (35 mmoles) of methyl 1-(2,2,2-trifluoroethoxy)-2-naphthoate, 2.9 g., (42 mmoles) of potassium hydroxide, 50 ml. of ethanol and 40 ml. of water is refluxed for one hour, chilled and acidified. The fluffy precipitate is collected, water washed, and air-dried. It is purified by recrystallization first from chloroform and then from aqueous alcohol, m.p. 171.5°-172° C.

1. additionA mixture of 10 g
2. temperaturechilled
3. customThe fluffy precipitate is collected
4. washwater washed
5. customair-dried
6. customIt is purified by recrystallization first from chloroform