HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → 2-(2,2,2-Trifluoroethoxy)benzoic Acid Hydrazide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Hydrazine | HCID 9321 | — |
| Reactant | Methyl 2-(2,2,2-trifluoroethoxy)benzoate | HCID 19622905 | — |
| Solvent | Water | HCID 962 | — |
| Product | 2-(2,2,2-Trifluoroethoxy)benzoic Acid Hydrazide | HCID 68130581 | — |
Reaction Steps
Methyl 2-(2,2,2-trifluoroethoxy)benzoate (1.22 g. 5.2 mmole), ethanol (15 ml.) and 5 ml. of 95 per cent hydrazine (4.75 g., 158 mmole) are refluxed for two hours, cooled, diluted with water (100 ml.) and cooled. The white solid product, 2-(2,2,2-trifluoroethoxy)benzoic acid hydrazide is recrystallized from ethanol, m.p. 102°-104°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03996280 |
| Source dataset | uspto-grants-1976_12 |
| ORD ID | ord-e71f53c5a9724943b613aded414047db |
| Source note | uspto-grants-1976_12 |