HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → Phenethylamine, alpha,alpha-dimethyl-4-dimethylamino-, dihydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Acetamide, N-[2-[4-(dimethylamino)phenyl]-1,1-dimethylethyl]- | HCID 2743045 | — |
| Solvent | Water | HCID 962 | — |
| Product | Phenethylamine, alpha,alpha-dimethyl-4-dimethylamino-, dihydrochloride | HCID 3043619 | — |
Reaction Steps
A solution of 3.5 of N-[α, α-dimethyl-β-(4-dimethylaminophenyl) ethyl]acetamide in a mixture of 25 ml of water and 25 ml of concentrated hydrochloric acid is reluxed for 16 hours. The solution is then evaporated under reduced pressure and the residue is recrystallized twice from methanol isopropyl ether. Yield: 1.1 g, m.p. 239,5°-240,5°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03996381 |
| Source dataset | uspto-grants-1976_12 |
| ORD ID | ord-b1f78afda1d940c9a3edc7cd831de829 |
| Source note | uspto-grants-1976_12 |