4-(5-Cyclopropyl-1,2-oxazol-3-yl)pyridine → HCID 68142299, compound

Participants

Reaction Steps

A solution of 3 g. of 4-(5-cyclopropyl-3-isoxazolyl)pyridine in 50 ml. of ethanol is treated with 0.5 g. of platinum oxide and the mixture is treated with hydrogen on a Parr apparatus at 44 psi for 5 hours at 25° C. The mixture is filtered and the filtrate is evaporated to dryness under reduced pressure to give a semi-solid residue which is recrystallized from ethyl acetate to give light tan crystals, melting point 159°-166° C.

Provenance & Evidence