Hydrochloric Acid → HCID 178522732, compound

Participants

Reaction Steps

4(2-Formyloxyethyl)-3,4-dihydro-3-oxo-N(1H-tetrazol-5-yl)-2-quinoxalinecarboxamide (Example 20d) (1.85 g) in water (100 ml) was treated with sodium hydroxide (5.9 ml., 2N) and the solution was stirred for 30 minutes at room temperature. Hydrochloric acid (6 ml., 2N) was added and the solid was collected and crystallised from aqueous dimethylformamide and dried. It had m.p. 269° (d).

Provenance & Evidence