HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Carbonate → HCID 21491289, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | Ethyl 4-ethyl-6-fluoro-3,4-dihydro-3-oxo-2-quinoxalinecarboxylate | HCID 86734255 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 21491289 | HCID 21491289 | — |
Reaction Steps
4-Ethyl-6-fluoro-3,4-dihydro-3-oxo-2-quinoxalinecarboxylic acid, ethyl ester (8 g) and sodium carbonate (0.25 g) in methanol (20 ml) and water (10 ml) were heated under reflux for 2 hours. The methanol was distilled off and the aqueous solution was acidified with hydrochloric acid and the solid was collected. It had m.p. 162.5°-164° (39%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03997535 |
| Source dataset | uspto-grants-1976_12 |
| ORD ID | ord-3f662c70f4384580922093e7c61c580b |
| Source note | uspto-grants-1976_12 |