HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzoic Acid → 4-Isopropylbenzoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzoic Acid | HCID 243 | — |
| Reactant | Cuminaldehyde | HCID 326 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | Potassium Permanganate | HCID 516875 | — |
| Catalyst | Dimethylformamide | HCID 6228 | — |
| Solvent | Sulfuric Acid | HCID 1118 | — |
| Product | 4-Isopropylbenzoyl chloride | HCID 2759486 | — |
Reaction Steps
p-isopropylbenzaldehyde is oxidized to the corresponding benzoic acid by using potassium permanganate in sulfuric acid as the oxidizing agent at low temperature. The acid is converted to the acid chloride using thionyl chloride with a trace of dimethylformamide as a catalyst to give p-isopropylbenzoyl chloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03997539 |
| Source dataset | uspto-grants-1976_12 |
| ORD ID | ord-62f40fb078594978a10936064201b5ba |
| Source note | uspto-grants-1976_12 |