Phenyl glycidyl ether → HCID 21430324, compound

HRID 1973624Notes

Reaction equation

HRID 1973624 reaction equation
[NH2:1][CH2:2][CH2:3][N:4]([C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)[C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1.[O:17]1[CH:19]([CH2:20][O:21][C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)[CH2:18]1>>[C:5]1([N:4]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[CH2:3][CH2:2][NH:1][CH2:18][CH:19]([OH:17])[CH2:20][O:21][C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1

Participants

3

Reactant 2

HCID 31217Phenyl glycidyl etherHCID 13222166N~1~,N~1~-Diphenylethane-1,2-diamine

Product 1

HCID 21430324HCID 21430324, compound

Procedure

A mixture of 6.4 g. N-(2-aminoethyl)-diphenylamine and 4.7 g. 1,2-epoxy-3-phenoxy-propane was heated for 10 minutes at 160°C. The reaction product was triturated with ether and then recrystallized from isopropanol. 4.7 g. (43% of theory) of colorless crystals of 1-(2-diphenylaminoethylamino)-2-hydroxy-3-phenoxy-propane were obtained; m.p. 95° - 96°C.

Workup

  1. additionA mixture of 6.4 g
  2. customThe reaction product was triturated with ether
  3. customrecrystallized from isopropanol

Sources & evidence

ORD record
ord-e461e31c606a41ba8bb0a9b3768d9b57
Source dataset
uspto-grants-1976_12
Patent number
US03998810

Reaction notes

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