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HRID1973707

反应详情

EQUATION

反应方程式

HRID 1973707 的结构方程式

REACTANTS

反应物

3
结构：Cl
HCID313

Hydrochloric Acid

ClH

结构：CO
HCID887

Methanol

CH4O

结构：C[C@H](CCC(=O)O)[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C
HCID221493

Cholic acid

C24H40O5

PRODUCTS

生成物

1
结构：COC(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C
HCID10960835

(3alpha,5beta,7alpha,12alpha)-Cholan-24-oic acid methyl ester

C25H42O5

PROCEDURE

实验过程

A mixture of 100 g cholic acid, 300 ml of methanol and 10 ml concentrated hydrochloric acid was refluxed on steam for 20 minutes. The resulting brown solution was refrigerated to induce crystallization. The crystals were collected, washed with 50 ml cold methanol, and dried to give 103 g methyl cholate, m.p. 153-154° C.

WORKUP

后处理

  1. temperaturewas refluxed on steam for 20 minutes
  2. customcrystallization
  3. customThe crystals were collected
  4. washwashed with 50 ml cold methanol
  5. customdried