HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 86734286, compound → 3alpha-Hydroxy-21-methyl-5alpha-pregnane-11,20-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 86734286 | HCID 86734286 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | 3alpha-Hydroxy-21-methyl-5alpha-pregnane-11,20-dione | HCID 86734287 | 93.6% |
Reaction Steps
3α-Hydroxy-21-methylene-5α-pregnane-11,20-dione(850 mg) was hydrogenated over 10% palladium on carbon catalyst (80 mg) in ethyl acetate for 1 hour. The catalyst was filtered off and the solvent removed in vacuo to give title compound (800 mg) as a white solid identical with the material of Example 1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03998829 |
| Source dataset | uspto-grants-1976_12 |
| ORD ID | ord-be99e8bd0d0b4f3fba08851e7dfb8a4c |
| Source note | uspto-grants-1976_12 |