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HRID1973720

反应详情

EQUATION

反应方程式

HRID 1973720 的结构方程式

REACTANTS

反应物

1
结构：C=CC(=O)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4C[C@H](O)CC[C@]4(C)[C@H]3C(=O)C[C@]12C
HCID86734286

未命名化合物

PRODUCTS

生成物

1
结构：CCC(=O)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4C[C@H](O)CC[C@]4(C)[C@H]3C(=O)C[C@]12C
HCID86734287

未命名化合物

收率 93.6%

AUXILIARIES

试剂、催化剂与溶剂

2
结构：[Pd]
催化剂HCID23938

Palladium

Pd

结构：CCOC(C)=O
溶剂HCID8857

Ethyl acetate

C4H8O2

PROCEDURE

实验过程

3α-Hydroxy-21-methylene-5α-pregnane-11,20-dione(850 mg) was hydrogenated over 10% palladium on carbon catalyst (80 mg) in ethyl acetate for 1 hour. The catalyst was filtered off and the solvent removed in vacuo to give title compound (800 mg) as a white solid identical with the material of Example 1.

WORKUP

后处理

  1. filtrationThe catalyst was filtered off
  2. customthe solvent removed in vacuo