Allylamine → HCID 21490726, compound

HRID 1973886Notes

Reaction equation

HRID 1973886 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[CH:5][CH:6]=[C:7]([C:13]([OH:15])=O)[C:8]=1[CH2:9][C:10]([OH:12])=O.[CH2:16]([NH2:19])[CH:17]=[CH2:18]>>[CH2:16]([N:19]1[C:10](=[O:12])[CH2:9][C:8]2[C:7](=[CH:6][CH:5]=[CH:4][C:3]=2[O:2][CH3:1])[C:13]1=[O:15])[CH:17]=[CH2:18]

Participants

3

Reactant 2

HCID 7853AllylamineHCID 12593122HCID 12593122, compound

Product 1

HCID 21490726HCID 21490726, compound

Procedure

A mixture of 6-methoxyhomophthalic acid (9.7 g., 0.05 mole) and allylamine (2.8 g., 0.05 mole) is heated by an oil bath until molten for 40 minutes. The mixture solidifies upon cooling and is recrystallized from isopropanol, giving 2-allyl-5-methoxyisoquinoline-1,3(2H,4H)-dione.

Workup

  1. temperatureis heated by an oil bath until molten for 40 minutes
  2. temperatureupon cooling
  3. customis recrystallized from isopropanol

Sources & evidence

ORD record
ord-35233e4bfddc47d99f8ab53a99480256
Source dataset
uspto-grants-1976_12
Patent number
US03998954

Reaction notes

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