HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetone → HCID 21490924, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetone | HCID 180 | — |
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | (5-Butyl-4-methoxypyridin-2-yl)methanol | HCID 13154061 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | HCID 21490924 | HCID 21490924 | — |
Reaction Steps
A solution of 2-hydroxymethyl-4-methoxy-5-n-butyl-pyridine in methanol is adjusted to pH 1 with hydrochloric acid in ether and evaporated to dryness. The water which still adheres is distilled off azeotropically with toluene. The residue thus obtained is digested with acetone and the crystalline product is filtered off. 2-Hydroxymethyl-4-methoxy-5-n-butyl-pyridine hydrochloride of melting point 136°-137° is thus obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03998955 |
| Source dataset | uspto-grants-1976_12 |
| ORD ID | ord-aeed5e8fff4941e58bb877b6c0ed57ff |
| Source note | uspto-grants-1976_12 |