Dimethylformamide → HCID 21488639, compound

HRID 1974043Notes

Reaction equation

HRID 1974043 reaction equation
[C:1]1([C:7]2[NH:8][C:9]3[C:14]([CH:15]=2)=[CH:13][CH:12]=[CH:11][CH:10]=3)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH3:16][N:17]([CH3:20])[CH:18]=O>>[C:1]1([C:7]2[NH:8][C:9]3[C:14]([C:15]=2[CH:16]2[N:8]([C:9]4[CH:10]=[CH:11][CH:12]=[CH:13][CH:14]=4)[CH2:7][CH2:18][N:17]2[C:20]2[CH:5]=[CH:6][CH:1]=[CH:2][CH:3]=2)=[CH:13][CH:12]=[CH:11][CH:10]=3)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

3

Reactant 2

HCID 6228DimethylformamideHCID 136982-Phenylindole

Product 1

HCID 21488639HCID 21488639, compound

Procedure

4.44 parts by weight of bis-[1,3-diphenyl-imidazolidin-(2)-ylidene] and 3.86 parts by weight of 2-phenylindole in 20 parts by volume of dimethylformamide are heated under nitrogen for 5 hours to boiling point. A little unreacted bis-[ 1,3-diphenyl-imidazolidin-(2)-ylidene] is filtered off while still warm, the solvent is removed partly in vacuo and 2-(2-phenylindol-3-yl)-1,3-diphenyl-imidazolidine is obtained in the form of colourless crystals melting at 237°-238° C (from toluene) ##STR15##

Workup

  1. filtrationA little unreacted bis-[ 1,3-diphenyl-imidazolidin-(2)-ylidene] is filtered off
  2. temperaturewhile still warm
  3. customthe solvent is removed partly in vacuo

Sources & evidence

ORD record
ord-279d4560353c44fd875193f4b10bca22
Source dataset
uspto-grants-1976_12
Patent number
US04000152

Reaction notes

Loading…