Hydrazine hydrate (1:1) → 2-Hydrazino-4-phenylquinoline

HRID 1974050Notes

Reaction equation

HRID 1974050 reaction equation
Cl[C:2]1[CH:11]=[C:10]([C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[N:3]=1.O.[NH2:19][NH2:20]>>[NH:19]([C:2]1[CH:11]=[C:10]([C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[N:3]=1)[NH2:20]

Participants

3

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 23066872-Chloro-4-phenylquinoline

Product 1

HCID 204855962-Hydrazino-4-phenylquinoline

Procedure

Refluxing a 2-chloro-4-phenylquinoline (1) with hydrazine hydrate to give a 2-hydrazino-4-phenylquinoline (II);

Sources & evidence

ORD record
ord-6eb817ef1fef430ab004d5d90b60c767
Source dataset
uspto-grants-1976_12
Patent number
US04000151

Reaction notes

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