Hydrazine hydrate (1:1) → HCID 21488596, compound

HRID 1974056Notes

Reaction equation

HRID 1974056 reaction equation
Cl[C:2]1[CH:11]=[C:10]([C:12]2[C:17]([F:18])=[CH:16][CH:15]=[CH:14][C:13]=2[F:19])[C:9]2[C:4](=[CH:5][CH:6]=[C:7]([Cl:20])[CH:8]=2)[N:3]=1.O.[NH2:22][NH2:23]>>[Cl:20][C:7]1[CH:8]=[C:9]2[C:4](=[CH:5][CH:6]=1)[N:3]=[C:2]([NH:22][NH2:23])[CH:11]=[C:10]2[C:12]1[C:17]([F:18])=[CH:16][CH:15]=[CH:14][C:13]=1[F:19]

Participants

3

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 21488591HCID 21488591, compound

Product 1

HCID 21488596HCID 21488596, compound

Procedure

In the manner given in Example 1, 2,6-dichloro-4-(2,6-difluorophenyl)quinoline is reacted at reflux with hydrazine hydrate to give 6-chloro-4-(2,6-difluorophenyl)-2-hydrazinoquinoline.

Workup

  1. customis reacted

Sources & evidence

ORD record
ord-8bbdc42411684177ae87f8ad3f2d2f5c
Source dataset
uspto-grants-1976_12
Patent number
US04000151

Reaction notes

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