HuagongsheHuagongshe Chemistry Print Report · For research reference only
7-Chloro-5-(2-chlorophenyl)-1-methyl-[1,2,4]triazolo[4,3-A]quinoline → (5-Chloro-2-(3-methyl-4H-1,2,4-triazol-4-yl)phenyl)(2-chlorophenyl)methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 7-Chloro-5-(2-chlorophenyl)-1-methyl-[1,2,4]triazolo[4,3-A]quinoline | HCID 21488587 | — |
| Reactant | Sodium periodate | HCID 23667635 | — |
| Catalyst | Ruthenium dioxide | HCID 82848 | — |
| Product | (5-Chloro-2-(3-methyl-4H-1,2,4-triazol-4-yl)phenyl)(2-chlorophenyl)methanone | HCID 626552 | — |
Reaction Steps
In the manner given in Example 3, 7-chloro-1-methyl-5-(o-chlorophenyl)-s-triazolo[4,3-a]quinoline is oxidized at low temperature with sodium periodate and ruthenium dioxide to give 2',5-dichloro-2-(3-methyl-4H-1,2,4-triazol-4-yl)benzophenone of melting point 147.5°-148.5° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04000151 |
| Source dataset | uspto-grants-1976_12 |
| ORD ID | ord-d34669a465af47c68897b3bf314e1a9c |
| Source note | uspto-grants-1976_12 |