Hydrazine hydrate (1:1) → HCID 21488594, compound

HRID 1974066Notes

Reaction equation

HRID 1974066 reaction equation
Cl[C:2]1[CH:11]=[C:10]([C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=2[Cl:18])[C:9]2[C:4](=[CH:5][CH:6]=[C:7]([F:19])[CH:8]=2)[N:3]=1.O.[NH2:21][NH2:22]>>[F:19][C:7]1[CH:8]=[C:9]2[C:4](=[CH:5][CH:6]=1)[N:3]=[C:2]([NH:21][NH2:22])[CH:11]=[C:10]2[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=1[Cl:18]

Participants

3

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 21488612HCID 21488612, compound

Product 1

HCID 21488594HCID 21488594, compound

Procedure

In the manner given in Example 1, 2-chloro-6-fluoro-4-(o-chlorophenyl)quinoline is reacted at reflux with hydrazine hydrate to give 6-fluoro-4-(o-chlorophenyl)-2-hydrazinoquinoline.

Workup

  1. customis reacted

Sources & evidence

ORD record
ord-ac71d21173634493aed2555117557b92
Source dataset
uspto-grants-1976_12
Patent number
US04000151

Reaction notes

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