Hydrazine hydrate (1:1) → HCID 21488600, compound

HRID 1974069Notes

Reaction equation

HRID 1974069 reaction equation
[F:1][C:2]([F:22])([F:21])[C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][CH:12]=1)[N:9]=[C:8](Cl)[CH:7]=[C:6]2[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][C:15]=1[Cl:20].O.[NH2:24][NH2:25]>>[F:1][C:2]([F:22])([F:21])[C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][CH:12]=1)[N:9]=[C:8]([NH:24][NH2:25])[CH:7]=[C:6]2[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][C:15]=1[Cl:20]

Participants

3

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 21488615HCID 21488615, compound

Product 1

HCID 21488600HCID 21488600, compound

Procedure

In the manner given in Example 1, 6-(trifluoromethyl)-2-chloro-4-(o-chlorophenyl)quinoline is reacted at reflux with hydrazine hydrate to give 6-(trifluoromethyl)-4-(o-chlorophenyl)-2-hydrazinoquinoline.

Workup

  1. customis reacted

Sources & evidence

ORD record
ord-d082b11ec0ea42e09ddd446045a37815
Source dataset
uspto-grants-1976_12
Patent number
US04000151

Reaction notes

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