Hydrochloric Acid → 1,1'-(2,5-Dimethylfuran-3,4-diyl)diethanone

HRID 1974081Notes

Reaction equation

HRID 1974081 reaction equation
[C:1]([CH:4]([C:12](=[O:14])[CH3:13])[CH:5]([C:9](=[O:11])[CH3:10])[C:6](=[O:8])[CH3:7])(=O)[CH3:2].Cl>>[CH3:7][C:6]1[O:8][C:1]([CH3:2])=[C:4]([C:12](=[O:14])[CH3:13])[C:5]=1[C:9](=[O:11])[CH3:10]

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 787303,4-Diacetyl-2,5-hexanedione

Product 1

HCID 3182851,1'-(2,5-Dimethylfuran-3,4-diyl)diethanone

Procedure

A mixture of 1.0 g. of 1,1,2,2-tetraacetylethane in 10 ml. of concentrated hydrochloric acid was stirred at room temperature for about 1 hour until a clear solution was obtained. The mixture was then poured onto ice and extracted with diethyl ether. The extracts were dried over sodium sulfate, taken to dryness, and the residue recrystallized from hexane to give 2,5-dimethyl-3,4-diacetylfuran, m.p. 75°-77° C.

Workup

  1. additionA mixture of 1.0 g
  2. customwas obtained
  3. additionThe mixture was then poured onto ice
  4. extractionextracted with diethyl ether
  5. dry with materialThe extracts were dried over sodium sulfate
  6. customthe residue recrystallized from hexane

Sources & evidence

ORD record
ord-e0be1fb23ef045f9953cc3f89ddb98fc
Source dataset
uspto-grants-1976_12
Patent number
US04000165

Reaction notes

Loading…