Methyl iodide → HCID 20560070, compound

HRID 1974085Notes

Reaction equation

HRID 1974085 reaction equation
[CH:1]([NH:3][C:4]1[CH:17]=[CH:16][CH:15]=[CH:14][C:5]=1[CH2:6][CH2:7][C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][N:9]=1)=[O:2].C[I:19].[I-].[NH+]1C=CC=C[CH:22]=1>CC(C)=O>[I-:19].[CH:1]([NH:3][C:4]1[CH:17]=[CH:16][CH:15]=[CH:14][C:5]=1[CH2:6][CH2:7][C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][N+:9]=1[CH3:22])=[O:2]

Participants

5

Reactant 3

HCID 6328Methyl iodideHCID 20559958HCID 20559958, compoundHCID 2186351518820-83-2

Product 1

HCID 20560070HCID 20560070, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Conditions

Temperature
5 °C

Procedure

A solution of 2-(o-formamidophenethyl)pyridine (55 g., 0.243 mole) and methyl iodide (38 g., 0.268 mole) in 500 ml. of acetone is refluxed for 20 hours. The mixture is cooled at 5° C. and filtered to provide 82 g. (92%) of the pyridinium iodide having melting point of 199.5°-201.5° C.

Workup

  1. filtrationfiltered
  2. customto provide 82 g

Sources & evidence

ORD record
ord-cc4efc4fb9ff41a18c02a1145f7e179d
Source dataset
uspto-grants-1976_12
Patent number
US04000143

Reaction notes

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