HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 3-furoate → N-{2-[2-(1-Methylpiperidin-2-yl)ethyl]phenyl}furan-3-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 3-furoate | HCID 69201 | — |
| Reactant | 2-(2-Aminophenethyl)-1-methylpiperidine | HCID 11085282 | — |
| Product | N-{2-[2-(1-Methylpiperidin-2-yl)ethyl]phenyl}furan-3-carboxamide | HCID 20559948 | — |
Reaction Steps
Reaction of ethyl furan-3-carboxylate prepared by the method of Boyd et al, Synthesis, 545, (Oct. 1971) with 2-(2-amino-phenethyl)-1-methylpiperidine according to the procedure of Example 115 provides 2'-[2-(1-methyl-2-piperidyl)ethyl]-3-furancarboxanilide, m.p. 114.5° - 115.5° C. (corr.), from isopropyl ether and then ethyl acetate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04000143 |
| Source dataset | uspto-grants-1976_12 |
| ORD ID | ord-81e8449a8a184f09a3cd4231a7fb1866 |
| Source note | uspto-grants-1976_12 |