Hydrazine hydrate (1:1) → HCID 21488600, compound

HRID 1974148Notes

Reaction equation

HRID 1974148 reaction equation
Cl[C:2]1[CH:11]=[C:10]([C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=2[Cl:18])[C:9]2[C:4](=[CH:5][CH:6]=[C:7]([C:19]([F:22])([F:21])[F:20])[CH:8]=2)[N:3]=1.O.[NH2:24][NH2:25]>>[F:20][C:19]([F:22])([F:21])[C:7]1[CH:8]=[C:9]2[C:4](=[CH:5][CH:6]=1)[N:3]=[C:2]([NH:24][NH2:25])[CH:11]=[C:10]2[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=1[Cl:18]

Participants

3

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 21488615HCID 21488615, compound

Product 1

HCID 21488600HCID 21488600, compound

Procedure

In the manner given in Example 1, 2-chloro-6 -(trifluoromethyl)-4-(o-chlorophenyl)quinoline is reacted with hydrazine hydrate at reflux to give 6-(trifluoromethyl)- 4-(o-chlorophenyl)-2-hydrazinoquinoline.

Workup

  1. temperatureat reflux

Sources & evidence

ORD record
ord-dc034badb2af4bc08eeb99b92176706a
Source dataset
uspto-grants-1976_12
Patent number
US04000153

Reaction notes

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