Formaldehyde → HCID 21488682, compound

HRID 1974151Notes

Reaction equation

HRID 1974151 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8](=[O:25])[C:9]1[CH:14]=[C:13]([C:15]([F:18])([F:17])[F:16])[CH:12]=[CH:11][C:10]=1[N:19]1[CH:23]=[N:22][N:21]=[C:20]1[CH3:24].[CH2:26]=[O:27]>C1(C)C(C)=CC=CC=1>[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8](=[O:25])[C:9]1[CH:14]=[C:13]([C:15]([F:18])([F:16])[F:17])[CH:12]=[CH:11][C:10]=1[N:19]1[C:20]([CH3:24])=[N:21][N:22]=[C:23]1[CH2:26][OH:27]

Participants

4

Reactant 2

HCID 712FormaldehydeHCID 21488590HCID 21488590, compound

Product 1

HCID 21488682HCID 21488682, compound

Reagents, catalysts & solvents 1

HCID 7237O-XyleneSolvent

Conditions

Temperature
122 °C

Procedure

In the manner given in Example 4, 2'-chloro-5-(trifluoromethyl)-2-(3-methyl-4H-1,2,4-triazol-4-yl)benzophenone, paraformaldehyde and xylene are warmed under nitrogen to about 122° C. to give 2'-chloro-5-(trifluoromethyl)-2-[3-(hydroxymethyl)-5-methyl-4H-1,2,4-triazol-4-yl]benzophenone.

Sources & evidence

ORD record
ord-da8a3748297e4ef3833ee1f85359ff73
Source dataset
uspto-grants-1976_12
Patent number
US04000153

Reaction notes

Loading…