1,2-Dichloro-3-{2-[(chloromethyl)sulfanyl]propan-2-yl}benzene → HCID 21489025, compound

HRID 1974249Notes

Reaction equation

HRID 1974249 reaction equation
[Cl:1][C:2]1[C:13]([Cl:14])=[CH:12][CH:11]=[CH:10][C:3]=1[C:4]([S:7][CH2:8]Cl)([CH3:6])[CH3:5].[P:15]([S-:21])(=[S:20])([O:18][CH3:19])[O:16][CH3:17].[Na+]>>[P:15]([S:21][CH2:8][S:7][C:4]([CH3:6])([CH3:5])[C:3]1[CH:10]=[CH:11][CH:12]=[C:13]([Cl:14])[C:2]=1[Cl:1])(=[S:20])([O:18][CH3:19])[O:16][CH3:17]

Participants

3

Reactant 2

HCID 214890641,2-Dichloro-3-{2-[(chloromethyl)sulfanyl]propan-2-yl}benzeneHCID 23683120Phosphorodithioic acid, O,O-dimethyl ester, sodium salt

Product 1

HCID 21489025HCID 21489025, compound

Procedure

Using chloromethyl 2,3-dichloro-α,α-dimethylbenzyl sulfide (prepared from 2,3-dichloro-α,α-dimethyl-α-toluenethiol obtained as in Example 1 from 2,3-dichloro-α,α-dimethylbenzyl alcohol) and stirring vigorously for 2 hours at 50° C. with a 10% excess of 50% aqueous sodium O,O-dimethyl phosphorodithioate solution gives a crude product which is purified as in Example 6 to give the pure, desired product as a colorless oil.

Workup

  1. customgives a crude product which
  2. customis purified as in Example 6

Sources & evidence

ORD record
ord-97bda681c53c44c0bdfa8480ad68315a
Source dataset
uspto-grants-1976_12
Patent number
US04000269

Reaction notes

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