Dimethylformamide → 3-Benzyloxy-5-methyl-4-oxo-2-[(1,2,3,4-tetrahydro-isoquinolin-2-yl)carbonyl]-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine

HRID 197427Notes

Reaction equation

HRID 197427 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[c:10]([C:20](=[O:21])[OH:22])[n:11][n:12]2[c:13]1[C:14](=[O:19])[N:15]([CH3:18])[CH2:16][CH2:17]2.[CH2:47]1[NH:48][CH2:49][CH2:50][c:51]2[cH:52][cH:53][cH:54][cH:55][c:56]21.[O:57]=[CH:58][N:59]([CH3:60])[CH3:61].[P-:23]([F:24])([F:25])([F:26])([F:27])([F:28])[F:29].[n:30]1([O:31][C:32]([N:33]([CH3:34])[CH3:35])=[N+:36]([CH3:37])[CH3:38])[c:39]2[n:40][cH:41][cH:42][cH:43][c:44]2[n:45][n:46]1>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[c:10]([C:20](=[O:21])[N:48]2[CH2:47][c:56]3[c:51]([cH:52][cH:53][cH:54][cH:55]3)[CH2:50][CH2:49]2)[n:11][n:12]2[c:13]1[C:14](=[O:19])[N:15]([CH3:18])[CH2:16][CH2:17]2

Participants

6

Reactant 5

HCID 6228DimethylformamideHCID 70461,2,3,4-TetrahydroisoquinolineHCID 9886HexafluorophosphateHCID 4641409(Dimethylamino)-N,N-dimethyl(3H-(1,2,3)triazolo(4,5-b)pyridin-3-yloxy)methaniminiumHCID 689513253-Benzyloxy-5-methyl-4-oxo-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-2-carboxylic acid

Product 1

HCID 689539593-Benzyloxy-5-methyl-4-oxo-2-[(1,2,3,4-tetrahydro-isoquinolin-2-yl)carbonyl]-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine

Sources & evidence

ORD record
ord-d0119ff63fc046c995172bbb3b0597dd
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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