3-Nitro-N-(pyridin-4-yl)pyridin-2-amine → HCID 12445535, compound

HRID 1974324Notes

Reaction equation

HRID 1974324 reaction equation
[N+:1]([C:4]1[C:5]([NH:10][C:11]2[CH:16]=[CH:15][N:14]=[CH:13][CH:12]=2)=[N:6][CH:7]=[CH:8][CH:9]=1)([O-])=O>[Pd].CO>[NH2:1][C:4]1[C:5]([NH:10][C:11]2[CH:16]=[CH:15][N:14]=[CH:13][CH:12]=2)=[N:6][CH:7]=[CH:8][CH:9]=1

Participants

4

Reactant 1

HCID 124453923-Nitro-N-(pyridin-4-yl)pyridin-2-amine

Product 1

HCID 12445535HCID 12445535, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

The nitro compound from Step A (1.0 g.) was hydrogenated in 60 ml. of methanol over 0.2 g. of 5% palladium on carbon catalyst. The catalyst was removed by filtration and the filtrate was evaporated to dryness.

Workup

  1. customThe catalyst was removed by filtration
  2. customthe filtrate was evaporated to dryness

Sources & evidence

ORD record
ord-ea124cf1a6c54326bf7e664de0c6bc0c
Source dataset
uspto-grants-1976_12
Patent number
US04000286

Reaction notes

Loading…