反应详情

In 200 milliliters of ethanol, 1 gram of sodium (0.04 mole) was reacted with 3.6 grams of 2-butanethiol (0.04 mole). The mixture was stirred for one-half hour. Then 4-chloro-5,7-dinitro-2-trifluoromethylbenzimidazole (6.2 grams; 0.02 mole) was added, and the resulting reaction mixture was stirred overnight, poured into water, acidified, and filtered to separate the desired 4-sec-butylthio-5,7-dinitro-2-trifluoromethylbenzimidazole. It was recrystallized twice from a mixture of benzene and an aliphatic hydrocarbon fraction boiling at 60°-80° C., m.p., 111°-15° C.

1. customthe resulting reaction mixture
2. stirringwas stirred overnight
3. filtrationfiltered
4. customto separate the desired 4-sec-butylthio-5,7-dinitro-2-trifluoromethylbenzimidazole
5. customIt was recrystallized twice from a mixture of benzene
6. customan aliphatic hydrocarbon fraction boiling at 60°-80° C., m.p., 111°-15° C.