Ethyl propiolate → 1-(4-Chloro-benzyl)-pyrazol-5-one

HRID 1974354노트

반응식

HRID 1974354 반응식
C(O[C:4](=[O:7])[C:5]#[CH:6])C.[Cl:8][C:9]1[CH:17]=[CH:16][C:12]([CH2:13][NH:14][NH2:15])=[CH:11][CH:10]=1>C(O)CCC>[Cl:8][C:9]1[CH:17]=[CH:16][C:12]([CH2:13][N:14]2[C:4](=[O:7])[CH:5]=[CH:6][NH:15]2)=[CH:11][CH:10]=1

참가 물질

4

반응물 2

HCID 12182Ethyl propiolateHCID 3015209(4-Chlorobenzyl)hydrazine

생성물 1

HCID 233342501-(4-Chloro-benzyl)-pyrazol-5-one

시약·촉매·용매 1

HCID 2631-Butanol용매

실험 절차

9.8 g (0.1 mol) of propiolic acid ethyl ester and 15.6 g (0.1 mol) of p-chlorobenzylhydrazine in 100 ml of n-butanol were heated for 8 hours under reflux.

후처리

  1. temperatureunder reflux

출처 및 근거

ORD 기록
ord-6ebfcfadf1e14a738f015867aa75a477
출처 데이터셋
uspto-grants-1976_12
특허 번호
US04000294

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