HRID1974430

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID1049

Pyridine

C5H5N

HCID6101

4-Methylbenzenesulfonic acid

C7H8O3S

HCID31275

1,4-Dioxane

C4H8O2

结构：CC(=O)O[C@H]1CC[C@H]2[C@H]3[C@H](CC[C@]12C)[C@H]1CC[C@@H](O)C=C1C[C@H]3C

HCID68131708

未命名化合物

PRODUCTS

生成物

结构：COC1(O[C@H]2C=C3C[C@@H](C)[C@@H]4[C@H](CC[C@]5(C)[C@@H](OC(C)=O)CC[C@@H]45)[C@H]3CC2)CCCCC1

HCID22795299

未命名化合物

PROCEDURE

实验过程

The compound 7α-methylestr-4-en-3α,17β-diol 17-acetate is dissolved in anhydrous dioxane and treated with pyridine, p-toluenesulfonate and cyclohexanone methyl enolether. Stirring is continued for a period of 3 hours. The solvent is removed in vacuo and the residue is crystallized from pentane resulting in the formation of the desired 7α-methyl-3α-(1'-methoxycyclohexyloxy)estr-4-en-17β-ol acetate.

WORKUP

后处理

customThe solvent is removed in vacuo
customthe residue is crystallized from pentane resulting in the formation of the desired 7α-methyl-3α-(1'-methoxycyclohexyloxy)estr-4-en-17β-ol acetate