反应详情

温度

130 °C

In DMF, 1 g of 6-fluoro-7-nitroquinoxaline-2,3-(1H,4H)-dione and 1.8 g of 2-methylimidazole were stirred with heating at 130° C. for 8 hours. The reaction mixture was then concentrated and diluted with water, whereupon crystals separated out. The crystals were recrystallized from DMF-water to provide 540 mg of 6-(2-methylimidazolyl)-7-nitroquinoxaline-2,3-(1H,4H)-dione.

1. concentrationThe reaction mixture was then concentrated
2. additiondiluted with water, whereupon crystals
3. customseparated out
4. customThe crystals were recrystallized from DMF-water