Potassium Nitrate → HCID 19101553, compound

HRID 1974484Notes

Reaction equation

HRID 1974484 reaction equation
[ClH:1].[N:2]1([C:7]2[CH:16]=[C:15]3[C:10]([NH:11][C:12](=[O:21])[C:13](=[O:20])[N:14]3[CH2:17][CH2:18][CH3:19])=[CH:9][CH:8]=2)[CH:6]=[CH:5][N:4]=[CH:3]1.[N+:22]([O-])([O-:24])=[O:23].[K+]>S(=O)(=O)(O)O>[ClH:1].[N:2]1([C:7]2[CH:16]=[C:15]3[C:10]([NH:11][C:12](=[O:21])[C:13](=[O:20])[N:14]3[CH2:17][CH2:18][CH3:19])=[CH:9][C:8]=2[N+:22]([O-:24])=[O:23])[CH:6]=[CH:5][N:4]=[CH:3]1

Participants

4

Reactant 2

HCID 24434Potassium NitrateHCID 19101592HCID 19101592, compound

Product 1

HCID 19101553HCID 19101553, compoundYield 78.5%

Reagents, catalysts & solvents 1

HCID 1118Sulfuric AcidSolvent

Procedure

To a solution of 1 g of 7-(1-imidazolyl)-1-n-propylquinoxaline-2,3-(1H,4H)-dione hydrochloride in 8 ml of sulfuric acid was added 0.4 g of potassium nitrate, and the mixture was stirred overnight. The reaction mixture was poured in ice-water and adjusted to pH 7. The resulting crystals were recrystallized from 1N-hydrochloric acid to provide 0.9 g of 7-(1-imidazolyl)-6-nitro-1-n-propylquinoxaline-2,3-(1H,4H)-dione hydrochloride.

Workup

  1. customThe resulting crystals were recrystallized from 1N-hydrochloric acid

Sources & evidence

ORD record
ord-20ebe5e129c04fe8b1faf16d50b327d4
Source dataset
uspto-grants-1994_02
Patent number
US05283244

Reaction notes

Loading…