Hydrochloric Acid → HCID 19101563, compound

Participants

Reaction Conditions

Reaction Steps

In 5 ml of 4N-hydrochloric acid was dissolved 250 mg of 1-(2-acetoxyethyl)-7-(1-imidazolyl)-6-nitroquinoxaline-2,3-(1H,4H)-dione of Example 17-14 and the solution was stirred at 100° C. for 3 hours. The reaction mixture was concentrated, followed by addition of methanol, whereupon crystals separated out. The crystals were recovered by filtration to provide 200 mg of 1-(2-hydroxyethyl)-7-(1-imidazolyl)-6-nitroquinoxaline-2,3-(1H,4H)-dione hydrochloride.

Provenance & Evidence