Chloroacetone → HCID 57304731, compound

Participants

Reaction Steps

1.5 g (0.0037 mol) of the compound from Example III and 5 ml of chloroacetone are heated with 10 ml of water at 100° C. in an oil bath for 30 minutes. The mixture is then neutralised with sodium bicarbonate solution and extracted with methylene chloride. After the extract has been dried with sodium sulphate, it is concentrated to dryness in vacuo, and the residue is recrystallised in diisopropyl ether.

Provenance & Evidence