Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Pyrrole | HCID 8027 | — |
| Reactant | 5-(Hydroxymethyl)-3-nitrobenzene-1,2-diol | HCID 18990374 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 18990361 | HCID 18990361 | — |
Reaction Steps
A solution containing 1.0 g of 3,4-dihydroxy-5-nitrobenzylalcohol and 5.0 ml of pyrrole in 3.0 ml of dioxane was heated for 5 h at 100° C. Water was added and the solution was extracted with dichloromethane. The solvent was evaporated and the residue was purified in a silicagel column using toluene-acetic acid-dioxane (18:1:1) mixture as an eluent. Yield 0.42 g (33%), m.p. 115°-118° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05283352 |
|---|
| Source dataset | uspto-grants-1994_02 |
|---|
| ORD ID | ord-da548f3fbfa24705b69d57bf669feb24 |
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| Source note | uspto-grants-1994_02 |
|---|
