Phenol → HCID 11199196, compound

HRID 1974781Notes

Reaction equation

HRID 1974781 reaction equation
C(Cl)Cl.[C:4]1([OH:10])[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1>C1(C)C=CC=CC=1>[OH:10][C:4]1[CH:9]=[CH:8][C:7]([C:4]2([C:7]3[CH:8]=[CH:9][C:4]([OH:10])=[CH:5][CH:6]=3)[CH2:9][CH2:8][CH:7]([C:7]3[CH:8]=[CH:9][C:4]([OH:10])=[CH:5][CH:6]=3)[CH2:6][CH2:5]2)=[CH:6][CH:5]=1

Participants

4

Reactant 2

HCID 996PhenolHCID 6344Dichloromethane

Product 1

HCID 11199196HCID 11199196, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent2×

Procedure

After heating, the thick paste was diluted with 450 mL toluene, cooled in an ice/water bath and isolated by filtration. It was treated with portions of toluene and methylene chloride until the amount of residual phenol was less than 1 area percent by HPLC analysis. The solid was isolated by filtration and was 90% pure by HPLC analysis, product weight, 57.7 g (76%).

Workup

  1. temperatureAfter heating
  2. temperaturecooled in an ice/water bath
  3. customisolated by filtration
  4. customThe solid was isolated by filtration

Sources & evidence

ORD record
ord-1a8181b4940e41139a0522d0d467934e
Source dataset
uspto-grants-1994_02
Patent number
US05283374

Reaction notes

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