反应详情

10 g (42.7 mmol) of 1-benzyl-3-ethylaminomethyl-3-hydroxypyrrolidine in 60 ml of methanol are hydrogenated using 2 g of palladium/active carbon (10%) at 92° C. and 107 bar. The catalyst is filtered off, the filtrate is concentrated and the residue is distilled.

1. customat 92° C.
2. filtrationThe catalyst is filtered off
3. concentrationthe filtrate is concentrated
4. distillationthe residue is distilled