HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Benzyl-3-ethylaminomethyl-3-hydroxypyrrolidine → 3-Ethylaminomethyl-3-hydroxypyrrolidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Benzyl-3-ethylaminomethyl-3-hydroxypyrrolidine | HCID 14578452 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 3-Ethylaminomethyl-3-hydroxypyrrolidine | HCID 14578450 | — |
Reaction Steps
10 g (42.7 mmol) of 1-benzyl-3-ethylaminomethyl-3-hydroxypyrrolidine in 60 ml of methanol are hydrogenated using 2 g of palladium/active carbon (10%) at 92° C. and 107 bar. The catalyst is filtered off, the filtrate is concentrated and the residue is distilled.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05284842 |
| Source dataset | uspto-grants-1994_02 |
| ORD ID | ord-8608d8dbac1a4d7683561f0da149e36d |
| Source note | uspto-grants-1994_02 |