HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylamine → 3-[(Dimethylamino)methyl]-1-(phenylmethyl)-3-pyrrolidinol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylamine | HCID 674 | — |
| Reactant | 5-Benzyl-1-oxa-5-azaspiro[2.4]heptane | HCID 11194805 | — |
| Product | 3-[(Dimethylamino)methyl]-1-(phenylmethyl)-3-pyrrolidinol | HCID 14578455 | — |
Reaction Steps
9.6 g (50 mmol) of 5-benzyl-5-aza-1-oxaspiro[2,4]heptane are added dropwise to 50 ml of dimethylamine solution (50%) and the mixture is stirred overnight at room temperature. The batch is then concentrated and the residue is distilled.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05284842 |
| Source dataset | uspto-grants-1994_02 |
| ORD ID | ord-3e8b83bf3e8c4926b150b61d4988bc0f |
| Source note | uspto-grants-1994_02 |