反应详情

9.4 g (39 mmol) of 1-benzyl-3-dimethylaminomethyl-3-hydroxypyrrolidine in 60 ml of methanol are hydrogenated using 2 g of palladium/active carbon (5%) at 100° C. and 90 bar. The catalyst is filtered off, the filtrate is concentrated and the residue is distilled.

1. customat 100° C.
2. filtrationThe catalyst is filtered off
3. concentrationthe filtrate is concentrated
4. distillationthe residue is distilled