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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1974890Generated: November 1, 2026

1-Cyclopropyl-6,7,8-trifluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid → HCID 14578482, compound

https://huagongshe.com/reaction/1974890

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Cyclopropyl-6,7,8-trifluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acidHCID 535414—
ReactantHCID 19382179HCID 19382179—
ProductHCID 14578482HCID 14578482—

Reaction Steps

1-Cyclopropyl-6,7,8-trifluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid is reacted analogously to Example 6 with 3-cyclopropylaminomethyl-3-hydroxypyrrolidine dihydrochloride to give 1-cyclopropyl-7-(3-cyclopropylaminomethyl-3-hydroxy-1-pyrrolidinyl)-6,8-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid of melting point 161°-162° (with decomposition).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05284842
Source datasetuspto-grants-1994_02
ORD IDord-ea171a236f0d446bbff167d9e3d79a5e
Source noteuspto-grants-1994_02